INT204086

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Context Info
Confidence 0.48
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.74
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (TNF, LEP) extracellular region (TNF, LEP) signal transduction (TNF)
plasma membrane (TNF) intracellular (TNF) extracellular matrix organization (TNF)
Anatomy Link Frequency
adipose tissue 2
TNF (Homo sapiens)
LEP (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 16 99.82 Very High Very High Very High
Inflammation 6 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
Parenteral administration 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Inflammatory stimuli 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 19 99.16 Very High Very High Very High
Weight Loss 6 98.28 Very High Very High Very High
Mycobacterial Infection 41 97.36 Very High Very High Very High
Anorexia 10 5.00 Very Low Very Low Very Low
Infection 10 5.00 Very Low Very Low Very Low
INFLAMMATION 8 5.00 Very Low Very Low Very Low
Fever 5 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low
Sepsis 3 5.00 Very Low Very Low Very Low
Cough 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Microbial products and cytokines such as TNF and IL-1 increase leptin expression dose dependently in adipose tissue.
TNF Positive_regulation (increase) of Gene_expression (expression) of leptin in adipose tissue associated with obesity and cytokine
1) Confidence 0.48 Published 2007 Journal Mediators of Inflammation Section Abstract Doc Link PMC1804295 Disease Relevance 0.74 Pain Relevance 0.10

General Comments

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