INT204087

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Context Info
Confidence 0.09
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 2.60
Pain Relevance 0.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL1B, LEP) extracellular region (IL1B, LEP) cytosol (IL1B)
signal transduction (IL1B) aging (IL1B) lipid metabolic process (LEP)
Anatomy Link Frequency
adipose tissue 2
IL1B (Homo sapiens)
LEP (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 32 99.66 Very High Very High Very High
Inflammation 12 97.16 Very High Very High Very High
Inflammatory stimuli 2 86.48 High High
rheumatoid arthritis 2 71.84 Quite High
Parenteral administration 2 66.96 Quite High
headache 2 44.48 Quite Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 38 99.16 Very High Very High Very High
Weight Loss 12 97.96 Very High Very High Very High
Cancer 4 97.96 Very High Very High Very High
Disease 8 97.52 Very High Very High Very High
INFLAMMATION 16 97.16 Very High Very High Very High
Mycobacterial Infection 82 97.04 Very High Very High Very High
Appetite Loss 2 96.52 Very High Very High Very High
Anorexia 20 96.00 Very High Very High Very High
Infection 20 78.96 Quite High
Fever 10 72.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
and cytokines such as TNF and IL-1 increase leptin expression dose
IL-1 Positive_regulation (increase) of Gene_expression (expression) of leptin associated with cytokine
1) Confidence 0.09 Published 2007 Journal Mediators of Inflammation Section Body Doc Link PMC1804295 Disease Relevance 1.86 Pain Relevance 0.44
Microbial products and cytokines such as TNF and IL-1 increase leptin expression dose dependently in adipose tissue.
IL-1 Positive_regulation (increase) of Gene_expression (expression) of leptin in adipose tissue associated with obesity and cytokine
2) Confidence 0.09 Published 2007 Journal Mediators of Inflammation Section Abstract Doc Link PMC1804295 Disease Relevance 0.74 Pain Relevance 0.10

General Comments

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