INT204138

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Context Info
Confidence 0.36
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 0.99
Pain Relevance 0.60

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (TSPO) mitochondrion (TSPO) aging (TSPO)
response to stress (TSPO)
Anatomy Link Frequency
liver 3
colon 1
TSPO (Homo sapiens)
Pain Link Frequency Relevance Heat
carbamazepine 8 99.00 Very High Very High Very High
Paracetamol 7 87.20 High High
diclofenac 12 85.72 High High
cINOD 7 82.68 Quite High
Analgesic 4 81.56 Quite High
COX2 2 5.00 Very Low Very Low Very Low
COX-2 inhibitor 2 5.00 Very Low Very Low Very Low
fluoxetine 2 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ulcers 2 97.82 Very High Very High Very High
Liver Cancer 2 96.52 Very High Very High Very High
INFLAMMATION 7 82.44 Quite High
Breast Cancer 74 81.36 Quite High
Colon Cancer 18 72.96 Quite High
Apoptosis 24 67.68 Quite High
Metastasis 4 47.56 Quite Low
Cancer 28 46.00 Quite Low
Hyperplasia 2 35.96 Quite Low
Aggression 12 34.96 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
-blockers atenolol (d) and metoprolol (e), the anti-ulcer agent ranitidine (f), the antiepileptic drug carbamazepine (g), and the psychiatric drug paroxetine (h)Fig. 3Removal during MBR and CAS treatment of the lipid regulator and cholesterol-lowering statin drugs gemfibrozil (a), bezafibrate (b), clofibric acid (c), and pravastatin (d), the diuretic hydrochlorothiazide (e), and the hypoglycaemic agent glibenclamide (f)
Regulation (3Removal) of Gene_expression (treatment) of MBR associated with ulcers and carbamazepine
1) Confidence 0.36 Published 2006 Journal Anal Bioanal Chem Section Body Doc Link PMC1805043 Disease Relevance 0.26 Pain Relevance 0.60
As for ACSL4, altered TSPO expression has also been involved in several pathological conditions including breast, colon and liver cancer [18], [19].
Regulation (altered) of Gene_expression (expression) of TSPO in liver associated with liver cancer
2) Confidence 0.22 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2978721 Disease Relevance 0.37 Pain Relevance 0
As for ACSL4, altered TSPO expression has also been involved in several pathological conditions including breast, colon and liver cancer [18], [19].
Regulation (altered) of in colon Gene_expression (expression) of TSPO in liver associated with liver cancer
3) Confidence 0.08 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2978721 Disease Relevance 0.37 Pain Relevance 0

General Comments

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