INT204171

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Context Info
Confidence 0.06
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.73
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Ide) mitochondrion (Ide) extracellular space (Ide)
ATPase activity (Ide) nucleus (Ide)
Anatomy Link Frequency
fat 2
pancreatic beta cells 2
Ide (Mus musculus)
Pain Link Frequency Relevance Heat
fibrosis 1 89.00 High High
Central nervous system 4 81.88 Quite High
imagery 31 53.68 Quite High
Neuropeptide 2 53.60 Quite High
agonist 35 5.00 Very Low Very Low Very Low
vagus nerve 12 5.00 Very Low Very Low Very Low
Intracerebroventricular 8 5.00 Very Low Very Low Very Low
antagonist 6 5.00 Very Low Very Low Very Low
isoflurane 3 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Insulin Resistance 2 100.00 Very High Very High Very High
Diabetes Mellitus 59 99.36 Very High Very High Very High
Diabetic Nephropathy 1 90.88 High High
Disease 1 89.88 High High
Fibrosis 1 89.00 High High
Pressure Volume 2 Under Development 1 88.80 High High
Cv Unclassified Under Development 2 86.16 High High
Congenital Anomalies 1 79.40 Quite High
Increased Venous Pressure Under Development 3 79.36 Quite High
Heart Disease 1 75.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This mechanism was impaired during high-fat diet–induced insulin resistance and diabetes and reverted upon central NO supplementation (4).
Negative_regulation (impaired) of Positive_regulation (induced) of insulin in fat associated with diabetes mellitus and insulin resistance
1) Confidence 0.06 Published 2008 Journal Diabetes Section Body Doc Link PMC2551665 Disease Relevance 0.44 Pain Relevance 0.07
Chemical induction of insulin deficiency by a cytotoxic agent for pancreatic beta cells, streptozotocin (STZ), produces a well-characterized model of type 1 diabetes [20].
Negative_regulation (deficiency) of Positive_regulation (induction) of insulin in pancreatic beta cells associated with diabetes mellitus
2) Confidence 0.06 Published 2007 Journal Cardiovasc Diabetol Section Body Doc Link PMC1805425 Disease Relevance 1.28 Pain Relevance 0.10

General Comments

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