INT204234

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.43
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.27
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (CDKN2A, TP53) DNA binding (CDKN2A, TP53) protein complex (CDKN2A, TP53)
cytoplasm (CDKN2A, TP53) cytosol (CDKN2A, TP53) nucleolus (CDKN2A, TP53)
CDKN2A (Homo sapiens)
TP53 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 82 50.00 Quite Low
aspirin 13 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Aneuploidy 24 99.94 Very High Very High Very High
Tetraploidy 18 99.64 Very High Very High Very High
Congenital Anomalies 75 99.38 Very High Very High Very High
Chromosomal Instability 2 90.56 High High
Adenocarcinoma 84 82.48 Quite High
Cancer 69 64.24 Quite High
Cleidocranial Dysplasia 14 5.00 Very Low Very Low Very Low
Esophageal Cancer 13 5.00 Very Low Very Low Very Low
INFLAMMATION 5 5.00 Very Low Very Low Very Low
Apoptosis 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We simultaneously measured DNA content abnormalities (tetraploidy and aneuploidy), inactivation of TP53 (mutation and LOH), and inactivation of CDKN2A (mutation, methylation, and LOH), all of which have been shown to be mechanistically related to neoplastic progression in BE [28,29,34,80–82].
CDKN2A Binding (inactivation) of TP53 associated with aneuploidy, tetraploidy and congenital anomalies
1) Confidence 0.43 Published 2007 Journal PLoS Medicine Section Body Doc Link PMC1808095 Disease Relevance 1.27 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox