INT204252

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Context Info
Confidence 0.04
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.92
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (NSMCE1)
Anatomy Link Frequency
brain 1
NSMCE1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 34 50.00 Quite Low
cytokine 25 46.40 Quite Low
Inflammatory stimuli 1 36.60 Quite Low
cva 5 5.00 Very Low Very Low Very Low
headache 4 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Paresthesia 2 5.00 Very Low Very Low Very Low
fifth nerve 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 52 99.78 Very High Very High Very High
Brain Injury 72 99.50 Very High Very High Very High
Rhinitis 10 96.44 Very High Very High Very High
Injury 45 91.24 High High
Pressure And Volume Under Development 5 90.92 High High
Necrosis 12 90.68 High High
Adhesions 39 83.28 Quite High
Histiocytic Sarcoma 66 77.40 Quite High
INFLAMMATION 47 50.00 Quite Low
Epstein-barr Virus 6 46.72 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although direct examination of cerebral leukocyte invasion was not possible in the present study, our recent findings in the same cohort of TBI patients showing marked elevations of serum S100B and NSE as indicators of brain damage after resuscitation with NS [44], are strongly suggestive of neuroinflammation, BBB impairment and cellular infiltration that may be ameliorated by HSD [45,46].
Positive_regulation (elevations) of NSE in brain associated with brain injury
1) Confidence 0.04 Published 2010 Journal J Neuroinflammation Section Body Doc Link PMC2819256 Disease Relevance 0.73 Pain Relevance 0
They were strongly positive for CD163 (Fig. 4), CD68, lysozyme, NSE, and vimentin.
Positive_regulation (positive) of NSE
2) Confidence 0.01 Published 2007 Journal Diagn Pathol Section Body Doc Link PMC1808440 Disease Relevance 0.33 Pain Relevance 0
Immunohistochemical staining in the tumor cells was positive for CD163, CD68, lysozyme, CD45, and NSE.
Positive_regulation (positive) of NSE associated with cancer
3) Confidence 0.01 Published 2007 Journal Diagn Pathol Section Abstract Doc Link PMC1808440 Disease Relevance 0.86 Pain Relevance 0

General Comments

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