INT204259

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Context Info
Confidence 0.24
First Reported 2007
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 3.29
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (CD163) plasma membrane (CD163)
Anatomy Link Frequency
histiocytes 1
immune cell 1
monocytes 1
CD163 (Homo sapiens)
Pain Link Frequency Relevance Heat
Arthritis 28 26.64 Quite Low
Pain 4 8.40 Low Low
rheumatoid arthritis 16 5.00 Very Low Very Low Very Low
Inflammation 12 5.00 Very Low Very Low Very Low
headache 4 5.00 Very Low Very Low Very Low
Paresthesia 2 5.00 Very Low Very Low Very Low
fifth nerve 2 5.00 Very Low Very Low Very Low
Nerve growth factor 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 52 94.20 High High
Confusion 2 92.84 High High
Necrosis 10 86.52 High High
Sarcoma 20 72.52 Quite High
Histiocytic Sarcoma 66 71.92 Quite High
Carcinoma 4 70.24 Quite High
Interdigitating Dendritic Cell Sarcoma 8 64.56 Quite High
Death 4 58.24 Quite High
Langerhans Cell Sarcoma 8 57.36 Quite High
Follicular Dendritic Cell Sarcoma 14 54.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The neoplastic cells demonstrated immunohistochemical staining characteristics similar to those of normal monocytes/histiocytes, namely strong immunoreactivity with CD163, CD68, lysozyme, NSE, and vimentin.
CD163 Binding (immunoreactivity) of in histiocytes
1) Confidence 0.24 Published 2007 Journal Diagn Pathol Section Body Doc Link PMC1808440 Disease Relevance 1.59 Pain Relevance 0
Before quantifying the different populations, we tested whether tissue digestion might influence the detection of immune cell markers, by exposing PBMCs to the procedure or its components and subsequently staining for CD3, CD14, CD163, and CD20 (see Table 2 for experiment set-up).
CD163 Spec (might) Binding (staining) of in immune cell
2) Confidence 0.18 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2875643 Disease Relevance 0.11 Pain Relevance 0
The neoplastic cells demonstrated immunohistochemical staining characteristics similar to those of normal monocytes/histiocytes, namely strong immunoreactivity with CD163, CD68, lysozyme, NSE, and vimentin.
CD163 Binding (immunoreactivity) of in monocytes
3) Confidence 0.08 Published 2007 Journal Diagn Pathol Section Body Doc Link PMC1808440 Disease Relevance 1.59 Pain Relevance 0

General Comments

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