INT204299

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Context Info
Confidence 0.06
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.22
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Bcl2, Aifm1) cytoplasm (Bcl2, Aifm1) cytosol (Bcl2, Aifm1)
nucleus (Bcl2, Aifm1) aging (Bcl2) cell morphogenesis (Bcl2)
Bcl2 (Rattus norvegicus)
Aifm1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Glutamate 1 83.44 Quite High
Glutamate receptor 6 52.16 Quite High
imagery 2 12.64 Low Low
tetrodotoxin 2 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
nMDA receptor 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 32 100.00 Very High Very High Very High
Neurodegenerative Disease 1 81.20 Quite High
Injury 5 69.60 Quite High
Death 43 67.60 Quite High
Hypoxia 2 67.44 Quite High
Brain Injury 1 38.84 Quite Low
Convulsion 1 38.00 Quite Low
Infection 3 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low
Cv General 4 Under Development 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The release of AIF in excitotoxicity and apoptosis is likewise inhibited by Bcl-2 [10,17], suggesting that the activation of BH3-only proteins may also be required to relieve a Bcl-2 inhibition of AIF release.
Bcl-2 Negative_regulation (inhibited) of Localization (release) of AIF associated with apoptosis
1) Confidence 0.06 Published 2007 Journal BMC Cell Biol Section Body Doc Link PMC1808451 Disease Relevance 1.22 Pain Relevance 0.07

General Comments

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