INT204321

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Context Info
Confidence 0.23
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.10
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (NOS3, SIRT1) cytoplasm (NOS3, SIRT1) nucleolus (NOS3, SIRT1)
cell differentiation (SIRT1) nucleoplasm (SIRT1) mitochondrion (SIRT1)
Anatomy Link Frequency
skeletal muscle 1
NOS3 (Homo sapiens)
SIRT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 11 98.92 Very High Very High Very High
Targeted Disruption 1 40.08 Quite Low
Stress 10 5.00 Very Low Very Low Very Low
Aging 8 5.00 Very Low Very Low Very Low
Overweight 6 5.00 Very Low Very Low Very Low
Weight Loss 2 5.00 Very Low Very Low Very Low
Chronic Disease 2 5.00 Very Low Very Low Very Low
Heart Disease 1 5.00 Very Low Very Low Very Low
Helminth Infection 1 5.00 Very Low Very Low Very Low
Diabetes Mellitus 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In murine white adipocytes NO treatment increases SIRT1 protein [7], suggesting eNOS may also be involved in regulating SIRT1 in skeletal muscle.
eNOS Regulation (regulating) of SIRT1 in skeletal muscle associated with obesity
1) Confidence 0.23 Published 2007 Journal PLoS Medicine Section Body Doc Link PMC1808482 Disease Relevance 0.10 Pain Relevance 0

General Comments

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