INT204343
From wiki-pain
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Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
Correlation analysis between mtTFA and p53 expression by using the Pearson test showed significant correlation in endometrioid adenocarcinomas (P? | |||||||||||||||
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Correlation analysis between mtTFA and p53 expression by using the Pearson test showed significant correlation in endometrioid adenocarcinomas (P? | |||||||||||||||
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Six months of caloric restriction caused an increase in the expression levels of TFAM and PPARGC1A and induced mitochondrial biogenesis. | |||||||||||||||
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M of DETA-NO increased the mRNA expression of TFAM (0.62 ± 0.1 versus 1.3 ± 0.1, p < 0.001) and induced mitochondrial biogenesis (indicated by MitotrackerGreen, Figure 3A). | |||||||||||||||
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The MannWhitney U test was used for comparison of clinicopathological variables with positive and negative mtTFA expression. | |||||||||||||||
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Six months of caloric restriction caused an increase in the expression levels of TFAM (the principal transcription factor involved in regulating mtDNA transcription) and PPARGC1A (Figure 1A and 1B), suggesting an induction of mitochondrial biogenesis. | |||||||||||||||
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Six months of caloric restriction caused an increase in the expression levels of TFAM (the principal transcription factor involved in regulating mtDNA transcription) and PPARGC1A (Figure 1A and 1B), suggesting an induction of mitochondrial biogenesis. | |||||||||||||||
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The activation of ERK1/2 and Akt in de-ATSC via hypoxia/DHP-d resulted in the induction of stemness transcription factor expression, and in particular, Rex1 expression (Figure 3A). | |||||||||||||||
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Our results show that ATSC can undergo an increase in developmental potential following reprogramming via the overexpression of the embryonic transcription factor, Rex1, Oct4, and Oct4-dependent Nanog and Sox2. | |||||||||||||||
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General Comments
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