INT204346

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.49
First Reported 2007
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 0.28
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (PPARGC1A) mRNA processing (PPARGC1A) RNA binding (PPARGC1A)
mitochondrion organization (PPARGC1A) nucleus (PPARGC1A) protein complex assembly (PPARGC1A)
Anatomy Link Frequency
muscle 4
PPARGC1A (Homo sapiens)
Pain Link Frequency Relevance Heat
Catecholamine 28 5.00 Very Low Very Low Very Low
tolerance 8 5.00 Very Low Very Low Very Low
Restless leg syndrome 2 5.00 Very Low Very Low Very Low
adenocard 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 1 98.96 Very High Very High Very High
Heart Rate Under Development 6 90.20 High High
Diabetes Mellitus 27 36.52 Quite Low
Apoptosis 1 34.68 Quite Low
Insulin Resistance 18 9.12 Low Low
Obesity 21 5.40 Low Low
Weight Loss 4 5.04 Very Low Very Low Very Low
Overweight 32 5.00 Very Low Very Low Very Low
Appetite Loss 15 5.00 Very Low Very Low Very Low
Stress 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In rodents, knockout of the eNOS gene abolishes the caloric restriction-induced expression of PPARGC1A and TFAM mRNA and mitochondrial protein content [7].
Positive_regulation (induced) of Transcription (expression) of PPARGC1A associated with targeted disruption
1) Confidence 0.49 Published 2007 Journal PLoS Medicine Section Body Doc Link PMC1808482 Disease Relevance 0.10 Pain Relevance 0
There is also evidence indicating that muscle aerobic capacity is increased following HIIE due to increases in PGC-1a mediated transcription [49] occurring via AMPK activation [50].
Positive_regulation (increases) of Transcription (transcription) of PGC-1a in muscle
2) Confidence 0.01 Published 2011 Journal Journal of Obesity Section Body Doc Link PMC2991639 Disease Relevance 0.09 Pain Relevance 0
There is also evidence indicating that muscle aerobic capacity is increased following HIIE due to increases in PGC-1a mediated transcription [49] occurring via AMPK activation [50].
Positive_regulation (mediated) of Transcription (transcription) of PGC-1a in muscle
3) Confidence 0.01 Published 2011 Journal Journal of Obesity Section Body Doc Link PMC2991639 Disease Relevance 0.09 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox