INT204356

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Context Info
Confidence 0.61
First Reported 2007
Last Reported 2007
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.29
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (SIRT1) nucleoplasm (SIRT1) mitochondrion (SIRT1)
nuclear envelope (SIRT1) histone binding (SIRT1) enzyme binding (SIRT1)
Anatomy Link Frequency
skeletal muscle 2
SIRT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Chronic Disease 2 82.48 Quite High
Weight Loss 2 78.08 Quite High
Overweight 6 75.84 Quite High
Obesity 11 54.56 Quite High
Stress 10 13.16 Low Low
Aging 8 5.00 Very Low Very Low Very Low
Heart Disease 1 5.00 Very Low Very Low Very Low
Helminth Infection 1 5.00 Very Low Very Low Very Low
Diabetes Mellitus 1 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Currently, there no data in human skeletal muscle on how caloric restriction may affect the expression of PPARGC1A and SIRT1, as well as mitochondrial number and function.
Spec (may) Regulation (affect) of Gene_expression (expression) of SIRT1 in skeletal muscle
1) Confidence 0.61 Published 2007 Journal PLoS Medicine Section Body Doc Link PMC1808482 Disease Relevance 0.29 Pain Relevance 0

General Comments

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