INT204442

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Context Info
Confidence 0.44
First Reported 2007
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.30
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Fmr1) RNA binding (Fmr1) nucleus (Fmr1)
cytoplasm (Fmr1)
Fmr1 (Mus musculus)
Fmr1 - I304N (1)
Pain Link Frequency Relevance Heat
Glutamate receptor 6 95.44 Very High Very High Very High
agonist 10 41.68 Quite Low
Hippocampus 3 5.00 Very Low Very Low Very Low
tetrodotoxin 1 5.00 Very Low Very Low Very Low
cerebral cortex 1 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
nMDA receptor antagonist 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
halothane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Repression 4 72.40 Quite High
Stress 1 64.16 Quite High
Congenital Anomalies 4 58.44 Quite High
Sprains And Strains 11 52.68 Quite High
Intellectual Impairment 15 52.04 Quite High
Alzheimer's Dementia 21 50.00 Quite Low
Fragile X Syndrome 21 50.00 Quite Low
Anxiety Disorder 5 44.04 Quite Low
Convulsion 5 39.44 Quite Low
Syndrome 30 37.88 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Both PSD-95 and FMRP mRNAs contain putative G-quartets in their 3?
Regulation (Both) of Gene_expression (mRNAs) of FMRP
1) Confidence 0.44 Published 2007 Journal PLoS Biology Section Body Doc Link PMC1808499 Disease Relevance 0.12 Pain Relevance 0.05
Alternatively, the effects on LTD could be due to a hypomorphic expression of I304N-FMRP.
Regulation (effects) of Gene_expression (expression) of I304N-FMRP (I304N)
2) Confidence 0.27 Published 2009 Journal PLoS Genetics Section Body Doc Link PMC2779495 Disease Relevance 0.18 Pain Relevance 0.03

General Comments

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