INT204563

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Context Info
Confidence 0.37
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 16
Total Number 16
Disease Relevance 12.10
Pain Relevance 1.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Mpo) extracellular space (Mpo) oxidoreductase activity (Mpo)
lysosome (Mpo)
Anatomy Link Frequency
macrophages 2
monocytes 1
neutrophils 1
Mpo (Mus musculus)
Pain Link Frequency Relevance Heat
withdrawal 14 98.96 Very High Very High Very High
Inflammation 348 94.24 High High
Inflammatory response 97 92.96 High High
Spinal cord 82 90.48 High High
antagonist 43 89.24 High High
cytokine 144 76.40 Quite High
metalloproteinase 20 73.28 Quite High
Angina 11 69.08 Quite High
anesthesia 9 69.04 Quite High
fibrosis 50 65.88 Quite High
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 141 100.00 Very High Very High Very High
Injury 477 99.92 Very High Very High Very High
Foreign Bodies 18 99.20 Very High Very High Very High
Coronary Artery Disease 10 98.88 Very High Very High Very High
Neurogenic Inflammation 6 94.24 High High
INFLAMMATION 439 92.56 High High
Myocardial Infarction 127 92.28 High High
Death 63 92.04 High High
Spinal Cord Injury 122 89.80 High High
Burns 80 88.56 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Previous studies have indicated increased MPO activity following NEP inhibition (Umeno et al. 1989; Barbara et al. 2003).
MPO Binding (activity) of associated with urological neuroanatomy
1) Confidence 0.37 Published 2009 Journal Toxicology Mechanisms and Methods Section Body Doc Link PMC2736052 Disease Relevance 1.62 Pain Relevance 0.22
MPO activity was measured spectrophotometrically as follows: 0.1 ml of supernatant was combined with 2.9 ml of 50 mM phosphate buffer containing 0.167 mg ml?
MPO Binding (activity) of associated with urological neuroanatomy
2) Confidence 0.36 Published 2007 Journal Evidence-based Complementary and Alternative Medicine Section Body Doc Link PMC1810372 Disease Relevance 0.92 Pain Relevance 0.15
Implant-associated myeloperoxidase (MPO) and non-specific esterase (NSE) were quantified to assess the numbers of adherent polymorphonuclear neutrophils [PMN] and macrophages/monocytes [MØ], respectively.
MPO Binding (associated) of in monocytes associated with urological neuroanatomy
3) Confidence 0.36 Published 2007 Journal J Transl Med Section Body Doc Link PMC1929055 Disease Relevance 0.85 Pain Relevance 0.21
MPO activity
MPO Binding (activity) of associated with urological neuroanatomy
4) Confidence 0.34 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2698136 Disease Relevance 0.83 Pain Relevance 0.20
MPO activity
MPO Binding (activity) of associated with urological neuroanatomy
5) Confidence 0.34 Published 2008 Journal International Journal of Biological Sciences Section Body Doc Link PMC2430988 Disease Relevance 0.91 Pain Relevance 0
Myeloperoxidase activity
Myeloperoxidase Binding (activity) of
6) Confidence 0.33 Published 2008 Journal J Inflamm (Lond) Section Body Doc Link PMC2267461 Disease Relevance 0.57 Pain Relevance 0
Myeloperoxidase assay
Myeloperoxidase Binding (assay) of
7) Confidence 0.33 Published 2008 Journal J Inflamm (Lond) Section Body Doc Link PMC2267461 Disease Relevance 0.37 Pain Relevance 0.04
Myeloperoxidase assay
Myeloperoxidase Binding (assay) of
8) Confidence 0.31 Published 2010 Journal Crit Care Section Body Doc Link PMC2887192 Disease Relevance 0 Pain Relevance 0
Two population studies show that MPO (and CRP) in healthy individuals are both associated with future development of CAD [101,102].
MPO Binding (associated) of associated with coronary artery disease and urological neuroanatomy
9) Confidence 0.30 Published 2010 Journal BMC Med Section Body Doc Link PMC2898678 Disease Relevance 2.02 Pain Relevance 0.19
Myeloperoxidase assay
Myeloperoxidase Binding (assay) of
10) Confidence 0.28 Published 2008 Journal Journal of Korean Medical Science Section Body Doc Link PMC2526424 Disease Relevance 0.16 Pain Relevance 0.16
Myeloperoxidase activity
Myeloperoxidase Binding (activity) of
11) Confidence 0.28 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2935363 Disease Relevance 0.63 Pain Relevance 0.09
MPO assay
MPO Binding (assay) of associated with urological neuroanatomy
12) Confidence 0.27 Published 2010 Journal Clinical Science (London, England : 1979) Section Body Doc Link PMC2999885 Disease Relevance 0.45 Pain Relevance 0
Myeloperoxidase assay
Myeloperoxidase Binding (assay) of
13) Confidence 0.19 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2951918 Disease Relevance 0 Pain Relevance 0.04
Implant-associated myeloperoxidase (MPO) and non-specific esterase (NSE) were quantified to assess the numbers of adherent polymorphonuclear neutrophils [PMN] and macrophages/monocytes [MØ], respectively.
MPO Binding (associated) of in macrophages associated with urological neuroanatomy
14) Confidence 0.12 Published 2007 Journal J Transl Med Section Body Doc Link PMC1929055 Disease Relevance 0.85 Pain Relevance 0.21
Cisplatin-induced AKI is associated with increased renal myeloperoxidase, which is produced by neutrophils and macrophages [45, 108].
myeloperoxidase Binding (associated) of in macrophages associated with injury
15) Confidence 0.11 Published 2009 Journal Mediators of Inflammation Section Body Doc Link PMC2825552 Disease Relevance 0.96 Pain Relevance 0.03
Cisplatin-induced AKI is associated with increased renal myeloperoxidase, which is produced by neutrophils and macrophages [45, 108].
myeloperoxidase Binding (associated) of in neutrophils associated with injury
16) Confidence 0.04 Published 2009 Journal Mediators of Inflammation Section Body Doc Link PMC2825552 Disease Relevance 0.96 Pain Relevance 0.03

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