INT204768

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Context Info
Confidence 0.11
First Reported 2007
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.25
Pain Relevance 0.41

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il23a) extracellular region (Il23a)
Anatomy Link Frequency
jejunum 2
dendritic cells 2
Il23a (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 81 97.56 Very High Very High Very High
agonist 12 93.60 High High
adenocard 1 80.24 Quite High
antagonist 9 70.92 Quite High
cytokine 90 62.32 Quite High
Inflammatory mediators 4 57.04 Quite High
chemokine 10 5.00 Very Low Very Low Very Low
rheumatoid arthritis 6 5.00 Very Low Very Low Very Low
Inflammatory response 5 5.00 Very Low Very Low Very Low
tolerance 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 86 97.56 Very High Very High Very High
Colitis 39 96.32 Very High Very High Very High
Infection 23 89.12 High High
Nematode Infection 1 80.80 Quite High
Targeted Disruption 3 73.36 Quite High
Food Poisoning 1 59.44 Quite High
Urological Neuroanatomy 7 51.64 Quite High
Weight Loss 3 49.88 Quite Low
Sprains And Strains 34 45.00 Quite Low
Helminth Infection 4 31.12 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We also observed the change of IL-23 expression in the jejunum of the Trichinella spiralis infected mice at different time points.
Regulation (change) of Gene_expression (expression) of IL-23 in jejunum
1) Confidence 0.11 Published 2009 Journal Mediators of Inflammation Section Body Doc Link PMC2786920 Disease Relevance 0.62 Pain Relevance 0.18
, IL-23 and COX-2 expression, while a downregulation of IL-12 and IL-17 expression was detected.
Regulation (detected) of Gene_expression (expression) of IL-23
2) Confidence 0.11 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1819555 Disease Relevance 0.63 Pain Relevance 0.15
In view of the ability of the aforementioned agents to elevate cAMP and to produce reciprocal effects on IL-12 and IL-23 output from dendritic cells, it is surprising that ATP?
Regulation (effects) of Gene_expression (output) of IL-23 in dendritic cells
3) Confidence 0.07 Published 2007 Journal Purinergic Signal Section Body Doc Link PMC2096759 Disease Relevance 0 Pain Relevance 0.09

General Comments

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