INT204789

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Context Info
Confidence 0.23
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.44
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Tlr2, Nod2) plasma membrane (Tlr2, Nod2) intracellular (Tlr2, Nod2)
cytoplasm (Tlr2, Nod2) cytosol (Nod2) enzyme binding (Nod2)
Tlr2 (Mus musculus)
Nod2 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 49 94.52 High High
Crohn's disease 1 58.20 Quite High
cytokine 8 5.00 Very Low Very Low Very Low
chemokine 6 5.00 Very Low Very Low Very Low
tolerance 5 5.00 Very Low Very Low Very Low
Inflammatory mediators 4 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Inflammatory stimuli 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 52 94.52 High High
Sprains And Strains 33 73.20 Quite High
Disease 2 58.20 Quite High
Inflammatory Bowel Disease 15 54.08 Quite High
Colitis 38 49.80 Quite Low
Graft Vs Host Disease 1 38.48 Quite Low
Autoimmune Disease 1 36.48 Quite Low
Injury 1 22.08 Low Low
Urological Neuroanatomy 7 5.00 Very Low Very Low Very Low
Weight Loss 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As suggested by Travasso et al [44], we could speculate that PGN from tolerogenic probiotic could impact on the TLR2 signaling cascade through NOD2 interaction.
TLR2 Binding (interaction) of NOD2
1) Confidence 0.23 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1819555 Disease Relevance 0.44 Pain Relevance 0.16

General Comments

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