INT204809

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Context Info
Confidence 0.45
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.60
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Xiap) nucleus (Xiap) intracellular (Xiap)
protein complex (Xiap) ligase activity (Xiap) cytoplasm (Xiap)
Anatomy Link Frequency
photoreceptor 2
retinas 2
Xiap (Rattus norvegicus)
Pain Link Frequency Relevance Heat
anesthesia 4 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
Immobilon 2 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 172 100.00 Very High Very High Very High
Phototoxic Dermatitis 2 61.76 Quite High
Retinal Degeneration 24 54.76 Quite High
Targeted Disruption 18 42.36 Quite Low
Retina Disease 50 40.12 Quite Low
Stress 8 17.40 Low Low
Death 28 5.00 Very Low Very Low Very Low
Disease 20 5.00 Very Low Very Low Very Low
Cataract 8 5.00 Very Low Very Low Very Low
Retinal Diseases 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Western blotting confirmed that the HA-tagged XIAP protein was overexpressed in the retinas of injected eyes and undetectable in the contralateral control eyes (Fig. 3A).
Positive_regulation (overexpressed) of Gene_expression (overexpressed) of XIAP protein in retinas associated with apoptosis
1) Confidence 0.45 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1819556 Disease Relevance 0.83 Pain Relevance 0
Furthermore, immunohistochemistry confirmed XIAP overexpression at sites of photoreceptor preservation (Fig 3B).
Positive_regulation (overexpression) of Gene_expression (overexpression) of XIAP in photoreceptor associated with apoptosis
2) Confidence 0.45 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1819556 Disease Relevance 0.77 Pain Relevance 0

General Comments

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