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Context Info
Confidence 0.20
First Reported 1990
Last Reported 1990
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (POMC, CCK) signal transduction (POMC, CCK) extracellular region (POMC, CCK)
small molecule metabolic process (POMC) cell-cell signaling (POMC) cytoplasm (POMC)
Anatomy Link Frequency
lymphocytes 1
POMC (Homo sapiens)
CCK (Homo sapiens)
Pain Link Frequency Relevance Heat
Cholecystokinin 7 100.00 Very High Very High Very High
Neuropeptide 1 75.00 Quite High
Serotonin 2 38.88 Quite Low
antagonist 2 37.36 Quite Low
Opioid 1 32.48 Quite Low
dopamine receptor 2 25.00 Low Low
agonist 2 25.00 Low Low
gABA 1 25.00 Low Low
antidepressant 1 25.00 Low Low
tricyclic antidepressant 1 25.00 Low Low


Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Both in rats and humans, beta-endorphin and cholecystokinin increase with age; also in vitro, after 48-h culturing, the concentrations of beta-endorphin and cholecystokinin in lymphocytes obtained from humans of different ages changed with the same pattern observed in ex vivo experiments.
beta-endorphin Positive_regulation (increase) of cholecystokinin in lymphocytes associated with cholecystokinin
1) Confidence 0.20 Published 1990 Journal Ann. N. Y. Acad. Sci. Section Abstract Doc Link 2143059 Disease Relevance 0 Pain Relevance 0.21

General Comments

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