INT204860

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Context Info
Confidence 0.67
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.83
Pain Relevance 0.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Litaf) Golgi apparatus (Litaf) lysosome (Litaf)
signal transducer activity (Litaf)
Litaf (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammatory response 7 99.58 Very High Very High Very High
Inflammation 37 92.72 High High
chemokine 3 90.28 High High
Central nervous system 16 85.44 High High
dexamethasone 4 74.72 Quite High
agonist 1 73.96 Quite High
Spinal cord 1 49.00 Quite Low
Demyelination 4 5.00 Very Low Very Low Very Low
ketamine 3 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 44 99.40 Very High Very High Very High
Shock 1 95.56 Very High Very High Very High
Injury 33 91.64 High High
Stress 3 90.88 High High
Death 58 90.40 High High
Apoptosis 31 87.20 High High
Optic Nerve Injuries 34 84.32 Quite High
Retina Disease 4 71.20 Quite High
Parkinson's Disease 1 26.72 Quite Low
Necrosis 5 10.32 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
There is a strong immune-inflammatory response [54] as seen by the upregulation of JAK2, Litaf, Stat 1, and caspase 11 among others.
Positive_regulation (upregulation) of Litaf associated with inflammatory response
1) Confidence 0.67 Published 2008 Journal Molecular Vision Section Body Doc Link PMC2426719 Disease Relevance 1.50 Pain Relevance 0.08
Ablation of glucocorticoid signaling also intensified induction of transcription regulator Litaf and Zfp36 and the regulator of JAK-STAT pathway Pim-1 and Socs3.
Positive_regulation (induction) of Litaf
2) Confidence 0.49 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1819560 Disease Relevance 0.33 Pain Relevance 0.43

General Comments

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