INT204904

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Context Info
Confidence 0.14
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.09
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Tlr4) hydrolase activity, acting on glycosyl bonds (Hexb) plasma membrane (Tlr4)
intracellular (Tlr4) carbohydrate metabolic process (Hexb) lysosome (Hexb)
Tlr4 (Mus musculus)
Hexb (Mus musculus)
Pain Link Frequency Relevance Heat
Central nervous system 15 84.76 Quite High
cytokine 3 51.24 Quite High
chemokine 3 50.80 Quite High
Inflammation 34 5.00 Very Low Very Low Very Low
dexamethasone 4 5.00 Very Low Very Low Very Low
Demyelination 4 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
cerebral cortex 1 5.00 Very Low Very Low Very Low
Buprenorphine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Repression 4 94.08 High High
Death 7 50.00 Quite Low
INFLAMMATION 37 5.00 Very Low Very Low Very Low
Infection 11 5.00 Very Low Very Low Very Low
Demyelinating Disease 6 5.00 Very Low Very Low Very Low
Meningitis 5 5.00 Very Low Very Low Very Low
Disease 5 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 3 5.00 Very Low Very Low Very Low
Bacterial Meningitis 2 5.00 Very Low Very Low Very Low
Pneumococcal Infection 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In this particular case, RU486 essentially prevented gene upregulation (Cd44, Stat1, Ch25h and Il1b) or downregulation (C1qa and Hexb) by LPS.
LPS Positive_regulation (upregulation) of Hexb
1) Confidence 0.14 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1819560 Disease Relevance 0.09 Pain Relevance 0.09

General Comments

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