INT204973

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Context Info
Confidence 0.23
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.62
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Park7) mitochondrion organization (Park7) response to stress (Park7)
cytoplasm (Park7) cell proliferation (Park7) cytosol (Park7)
Park7 (Mus musculus)
Pain Link Frequency Relevance Heat
ischemia 1 62.32 Quite High
Neuropathic pain 9 5.00 Very Low Very Low Very Low
Calcium channel 8 5.00 Very Low Very Low Very Low
dorsal root ganglion 7 5.00 Very Low Very Low Very Low
sodium channel 6 5.00 Very Low Very Low Very Low
nav1.3 6 5.00 Very Low Very Low Very Low
nav1.8 6 5.00 Very Low Very Low Very Low
Dopamine 5 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Parkinson's Disease 6 100.00 Very High Very High Very High
Stress 3 98.60 Very High Very High Very High
Disease 11 96.52 Very High Very High Very High
Neuroma 79 86.24 High High
Targeted Disruption 48 84.32 Quite High
Nervous System Injury 11 78.28 Quite High
Necrosis 1 71.28 Quite High
Cancer 1 70.92 Quite High
Hypoxia 1 63.44 Quite High
Brain Hemorrhage 1 62.80 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Here we tested the third strategy in adult mice in which the PTEN-induced putative kinase 1 (PINK1) gene, a Parkinson disease (PD)-associated gene, was targeted.
Positive_regulation (induced) of Parkinson associated with parkinson's disease
1) Confidence 0.23 Published 2007 Journal International Journal of Biological Sciences Section Body Doc Link PMC1820878 Disease Relevance 0.93 Pain Relevance 0
Under oxidising conditions, DJ-1 is activated by the modification of cysteine residues to cysteine-sulfinic and cysteine-sulfonic acids to exert its protective effects [29,30].
Positive_regulation (activated) of DJ-1
2) Confidence 0.05 Published 2008 Journal Mol Pain Section Body Doc Link PMC2525634 Disease Relevance 0.68 Pain Relevance 0.03

General Comments

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