INT204990

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Context Info
Confidence 0.24
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.79
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Park7) mitochondrion organization (Park7) response to stress (Park7)
cytoplasm (Park7) cell proliferation (Park7) cytosol (Park7)
Park7 (Mus musculus)
Pain Link Frequency Relevance Heat
Pain 3 53.76 Quite High
sodium channel 6 40.80 Quite Low
Calcium channel 8 37.60 Quite Low
Neuropathic pain 9 5.00 Very Low Very Low Very Low
dorsal root ganglion 7 5.00 Very Low Very Low Very Low
nav1.3 6 5.00 Very Low Very Low Very Low
nav1.8 6 5.00 Very Low Very Low Very Low
Dopamine 5 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Parkinson's Disease 6 100.00 Very High Very High Very High
Neuroma 79 99.44 Very High Very High Very High
Disease 11 90.64 High High
Targeted Disruption 48 84.32 Quite High
Reprotox - General 3 1 58.68 Quite High
Death 8 58.08 Quite High
Epilepsy 1 54.64 Quite High
Pain 3 53.76 Quite High
Contagious Ecthyma 3 16.00 Low Low
Nervous System Injury 11 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Here we tested the third strategy in adult mice in which the PTEN-induced putative kinase 1 (PINK1) gene, a Parkinson disease (PD)-associated gene, was targeted.
Positive_regulation (induced) of Gene_expression (disease) of Parkinson associated with parkinson's disease
1) Confidence 0.24 Published 2007 Journal International Journal of Biological Sciences Section Body Doc Link PMC1820878 Disease Relevance 0.94 Pain Relevance 0
The expression of protein DJ-1 increased with time of neuroma formation as shown from the 2D-DIGE/MS profiling of mouse samples (Figure 3).
Positive_regulation (increased) of Gene_expression (expression) of DJ-1 associated with neuroma
2) Confidence 0.04 Published 2008 Journal Mol Pain Section Body Doc Link PMC2525634 Disease Relevance 0.85 Pain Relevance 0.05

General Comments

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