INT205031

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.45
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.11
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (Crhr2) endoplasmic reticulum (Crhr2) signal transducer activity (Crhr2)
response to stress (Crh) cytoplasm (Crh) extracellular space (Crh)
Crh (Mus musculus)
Crhr2 (Mus musculus)
Pain Link Frequency Relevance Heat
depression 4 76.64 Quite High
Neuropeptide 4 59.04 Quite High
antagonist 14 5.00 Very Low Very Low Very Low
gABA 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
isoflurane 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Anxiety Disorder 46 97.84 Very High Very High Very High
Stress 8 97.12 Very High Very High Very High
Aggression 110 92.40 High High
Targeted Disruption 30 83.12 Quite High
Depression 4 76.64 Quite High
Lung Cancer 8 35.68 Quite Low
Sprains And Strains 16 5.00 Very Low Very Low Very Low
Death 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CRF acts primarily on CRFR1 [11-13], but can also activate CRF receptor 2 (CRFR2) with less efficacy [14,15].
CRF Positive_regulation (activate) of CRFR2
1) Confidence 0.45 Published 2007 Journal BMC Neurosci Section Body Doc Link PMC1821036 Disease Relevance 0.96 Pain Relevance 0.03
Because CRF and its related peptides, Ucn 1 and 3, can activate CRFR2 [14,20-22], it is possible that increased activation of CRFR2 compensates for the loss of CRFR1 and contributes to alterations in maternal care.
CRF Positive_regulation (activate) of CRFR2
2) Confidence 0.45 Published 2007 Journal BMC Neurosci Section Body Doc Link PMC1821036 Disease Relevance 0.15 Pain Relevance 0.08

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox