INT205051

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Context Info
Confidence 0.36
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 3.02
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (MMP3, TIMP1) peptidase activity (MMP3) extracellular space (MMP3)
aging (TIMP1) proteinaceous extracellular matrix (MMP3) nucleus (MMP3)
Anatomy Link Frequency
1A2 2
MMP3 (Homo sapiens)
TIMP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 6 100.00 Very High Very High Very High
Somatostatin 2 11.92 Low Low
Chronic pancreatitis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fibrosis 6 98.24 Very High Very High Very High
Adenocarcinoma 134 94.84 High High
Islet Cell Adenoma 58 93.20 High High
Pancreatic Cancer 54 92.84 High High
Cancer 82 82.32 Quite High
Lymphatic System Cancer 10 81.12 Quite High
Sarcoma 4 80.32 Quite High
Giant Cell Tumors 4 78.32 Quite High
Thyroid Neoplasm 2 59.12 Quite High
Skin Cancer 2 57.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These genes included osteonectin (SPARC), fibronectin (FN1), versican (CSPG2), and collagen type 1A2 (COL1A2), tissue inhibitor of metalloproteinase 1 (TIMP1), biglycan (BGN), matrix metalloproteinase 2 (MMP2), and stromelysin-1 (MMP3) [5], [36]–[38].
MMP3 Negative_regulation (inhibitor) of TIMP1 in 1A2 associated with metalloproteinase
1) Confidence 0.36 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1824711 Disease Relevance 1.51 Pain Relevance 0.10
These genes included osteonectin (SPARC), fibronectin (FN1), versican (CSPG2), and collagen type 1A2 (COL1A2), tissue inhibitor of metalloproteinase 1 (TIMP1), biglycan (BGN), matrix metalloproteinase 2 (MMP2), and stromelysin-1 (MMP3) [5], [36]–[38].
MMP3 Negative_regulation (inhibitor) of metalloproteinase 1 in 1A2 associated with metalloproteinase
2) Confidence 0.31 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1824711 Disease Relevance 1.51 Pain Relevance 0.10

General Comments

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