INT205135

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Context Info
Confidence 0.05
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.35
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (APOE, APP) cytoplasm (APOE, APP) cell death (APOE, APP)
extracellular region (APOE, APP) plasma membrane (APOE, APP) small molecule metabolic process (APOE)
APOE (Homo sapiens)
APP (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 1 94.96 High High
cerebral cortex 2 58.64 Quite High
amygdala 13 5.00 Very Low Very Low Very Low
Pyramidal cell 3 5.00 Very Low Very Low Very Low
Hippocampus 2 5.00 Very Low Very Low Very Low
Enkephalin 1 5.00 Very Low Very Low Very Low
insula 1 5.00 Very Low Very Low Very Low
Thalamus 1 5.00 Very Low Very Low Very Low
medulla 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Alzheimer's Dementia 11 98.52 Very High Very High Very High
INFLAMMATION 1 94.96 High High
Disease 69 66.76 Quite High
Amyloidosis 8 50.00 Quite Low
Down Syndrome 35 17.40 Low Low
Cognitive Disorder 4 5.00 Very Low Very Low Very Low
Aging 4 5.00 Very Low Very Low Very Low
Amyloid Plaque 4 5.00 Very Low Very Low Very Low
Toxicity 2 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
APP tg mice crossed with apo-E knockouts reduces significantly the amyloid load [3].
apo-E Binding (crossed) of APP associated with alzheimer's dementia
1) Confidence 0.05 Published 2007 Journal Acta Neuropathol Section Body Doc Link PMC1824787 Disease Relevance 0.35 Pain Relevance 0.08

General Comments

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