INT205153

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Context Info
Confidence 0.14
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.57
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (SPP1, MMP9) extracellular region (SPP1, MMP9) peptidase activity (MMP9)
proteinaceous extracellular matrix (MMP9) cell adhesion (SPP1) extracellular matrix organization (MMP9)
SPP1 (Homo sapiens)
MMP9 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 30 49.12 Quite Low
Pain 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 62 77.84 Quite High
Metastasis 34 75.60 Quite High
Prostate Cancer 80 75.00 Quite High
Injury 28 74.64 Quite High
Adhesions 14 5.00 Very Low Very Low Very Low
Hypercalcemia 10 5.00 Very Low Very Low Very Low
Skin Cancer 10 5.00 Very Low Very Low Very Low
Apoptosis 8 5.00 Very Low Very Low Very Low
Carcinoma 6 5.00 Very Low Very Low Very Low
Cytomegalovirus Infection 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, zymography analysis demonstrated that the levels of MMP-9 activity in the conditioned media reflect the CD44 surface expression pattern of the PC3 cell lines; 4) although MMP-9 and MMP-2 are secreted by PC3 cells, only the secretion of MMP-9 is regulated by OPN expression.
Gene_expression (expression) of OPN Regulation (regulated) of Localization (secretion) of MMP-9
1) Confidence 0.14 Published 2007 Journal Mol Cancer Section Abstract Doc Link PMC1828067 Disease Relevance 0.27 Pain Relevance 0
MMP-9 activity but not the secreted level of MMP-9 is affected by BP treatment or OPN expression.
Gene_expression (expression) of OPN Regulation (affected) of Localization (secreted) of MMP-9
2) Confidence 0.14 Published 2007 Journal Mol Cancer Section Body Doc Link PMC1828067 Disease Relevance 0.30 Pain Relevance 0

General Comments

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