INT205156

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Context Info
Confidence 0.51
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.24
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (MMP9) extracellular space (MMP9) extracellular region (MMP9)
proteinaceous extracellular matrix (MMP9) cell adhesion (CD44) plasma membrane (CD44)
CD44 (Homo sapiens)
MMP9 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 15 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Prostate Cancer 40 86.56 High High
Adenocarcinoma 1 76.40 Quite High
Renal Disease 1 72.96 Quite High
Genomic Instability 1 28.24 Quite Low
Cancer 31 7.56 Low Low
Metastasis 17 5.00 Very Low Very Low Very Low
Injury 14 5.00 Very Low Very Low Very Low
Adhesions 7 5.00 Very Low Very Low Very Low
Hypercalcemia 5 5.00 Very Low Very Low Very Low
Skin Cancer 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A significant increase in the coclustering of CD44 and MMP-9 on the cell surface of PC3/OPN cells as compared with PC3 cells (Figure 5A and 5B) suggest a plausible mechanism of activation of MMP-9 by CD44.


CD44 Positive_regulation (activation) of MMP-9
1) Confidence 0.51 Published 2007 Journal Mol Cancer Section Body Doc Link PMC1828067 Disease Relevance 0.24 Pain Relevance 0

General Comments

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