INT205211

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Context Info
Confidence 0.54
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.69
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

structural molecule activity (Cldn4) plasma membrane (Cldn4) molecular_function (Cldn4)
Anatomy Link Frequency
lateral surface 2
ileum 1
Cldn4 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ischemia 84 98.24 Very High Very High Very High
cytokine 6 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Reperfusion Injury 63 99.00 Very High Very High Very High
Cv Unclassified Under Development 72 98.24 Very High Very High Very High
Cv General 4 Under Development 12 33.92 Quite Low
Disseminated Intravascular Coagulation 6 5.00 Very Low Very Low Very Low
Enteropathy 3 5.00 Very Low Very Low Very Low
Body Weight 3 5.00 Very Low Very Low Very Low
Necrosis 3 5.00 Very Low Very Low Very Low
Sepsis 3 5.00 Very Low Very Low Very Low
Injury 3 5.00 Very Low Very Low Very Low
Inflammatory Bowel Disease 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the villi, claudin-4 was localized at the lateral surface of the cell, whereas in the crypts it was localized to the apical side of the cell-cell contact (Fig. 5O); this pattern was similar to that observed in the control.


Localization (localized) of claudin-4 in lateral surface
1) Confidence 0.54 Published 2006 Journal Acta Histochemica et Cytochemica Section Body Doc Link PMC1828083 Disease Relevance 0 Pain Relevance 0
The present results of claudin-4 localization at lateral surface of the cells in the normal villi are consistent with those reported by Rahner et al. [13], which demonstrated the specificity of the claudin-4 antibody we used.
Localization (localization) of claudin-4 in lateral surface
2) Confidence 0.54 Published 2006 Journal Acta Histochemica et Cytochemica Section Body Doc Link PMC1828083 Disease Relevance 0.31 Pain Relevance 0.08
In contrast to ZO-1, occludin and claudin-1, -3, and -5, claudin-4 was unique not only in the localization in the control ileum but also in changes of expression during ischemia-reperfusion injury.
Localization (localization) of claudin-4 in ileum associated with reperfusion injury and ischemia
3) Confidence 0.44 Published 2006 Journal Acta Histochemica et Cytochemica Section Body Doc Link PMC1828083 Disease Relevance 0.38 Pain Relevance 0.11

General Comments

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