INT205445

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Context Info
Confidence 0.71
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 6
Disease Relevance 0.73
Pain Relevance 0.26

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cell differentiation (SORT1) endosome (SORT1) transport (SORT1)
Golgi apparatus (SORT1) endoplasmic reticulum (SORT1) enzyme binding (SORT1)
Anatomy Link Frequency
osteoblasts 1
brain 1
lung 1
heart 1
placenta 1
SORT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Spinal cord 6 94.16 High High
dexamethasone 12 5.00 Very Low Very Low Very Low
Pain 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoporosis 72 82.12 Quite High
Spinal Cord Diseases 6 76.44 Quite High
Shock 6 48.72 Quite Low
Aging 6 23.56 Low Low
Adhesions 18 5.00 Very Low Very Low Very Low
Obesity 18 5.00 Very Low Very Low Very Low
Reprotox - General 1 18 5.00 Very Low Very Low Very Low
Calcification 6 5.00 Very Low Very Low Very Low
Infarction 6 5.00 Very Low Very Low Very Low
Communicable Diseases 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Further studies are necessary to quantify the expression of ID4, SORT-1 and CRYAB in primary human osteoblasts and other cell types and to identify the role of these genes in osteogenesis.
Gene_expression (expression) of SORT-1 in osteoblasts
1) Confidence 0.71 Published 2007 Journal BMC Genomics Section Body Doc Link PMC1829400 Disease Relevance 0 Pain Relevance 0.04
The expression of sortilin1 is ubiquitous; it has been observed in heart, brain, placenta, lung, skeletal, muscle, pancreas, prostate, testis, small intestine, thyroid, and spinal cord, whereas its expression in bone marrow could not be detected [50].
Gene_expression (expression) of sortilin1 in placenta associated with spinal cord
2) Confidence 0.71 Published 2007 Journal BMC Genomics Section Body Doc Link PMC1829400 Disease Relevance 0.14 Pain Relevance 0.05
The expression of SORT1 was increasing until day seven and then slowly decreasing.
Gene_expression (expression) of SORT1
3) Confidence 0.71 Published 2007 Journal BMC Genomics Section Body Doc Link PMC1829400 Disease Relevance 0.16 Pain Relevance 0.04
The expression of sortilin1 is ubiquitous; it has been observed in heart, brain, placenta, lung, skeletal, muscle, pancreas, prostate, testis, small intestine, thyroid, and spinal cord, whereas its expression in bone marrow could not be detected [50].
Gene_expression (expression) of sortilin1 in heart associated with spinal cord
4) Confidence 0.24 Published 2007 Journal BMC Genomics Section Body Doc Link PMC1829400 Disease Relevance 0.14 Pain Relevance 0.05
The expression of sortilin1 is ubiquitous; it has been observed in heart, brain, placenta, lung, skeletal, muscle, pancreas, prostate, testis, small intestine, thyroid, and spinal cord, whereas its expression in bone marrow could not be detected [50].
Gene_expression (expression) of sortilin1 in brain associated with spinal cord
5) Confidence 0.24 Published 2007 Journal BMC Genomics Section Body Doc Link PMC1829400 Disease Relevance 0.14 Pain Relevance 0.05
The expression of sortilin1 is ubiquitous; it has been observed in heart, brain, placenta, lung, skeletal, muscle, pancreas, prostate, testis, small intestine, thyroid, and spinal cord, whereas its expression in bone marrow could not be detected [50].
Gene_expression (expression) of sortilin1 in lung associated with spinal cord
6) Confidence 0.24 Published 2007 Journal BMC Genomics Section Body Doc Link PMC1829400 Disease Relevance 0.14 Pain Relevance 0.05

General Comments

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