INT20549

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Context Info
Confidence 0.19
First Reported 1990
Last Reported 1990
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.06
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL1B, FN1) extracellular region (IL1B, FN1) aging (IL1B)
cell-cell signaling (IL1B) cytosol (IL1B) signal transduction (IL1B)
Anatomy Link Frequency
cartilage 1
IL1B (Homo sapiens)
FN1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 3 90.08 High High
Potency 1 84.48 Quite High
Inflammation 1 25.00 Low Low
Disease Link Frequency Relevance Heat
INFLAMMATION 2 64.80 Quite High
Arthropathy 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast, expression of types I and III collagens and fibronectin, matrix components produced by chondrocytes that have lost cartilage-specific phenotype, is increased by IL-1, particularly when IL-1-stimulated synthesis of PGE2 is blocked by a prostaglandin synthetase inhibitor.
IL-1 Positive_regulation (increased) of fibronectin in cartilage
1) Confidence 0.19 Published 1990 Journal Eur J Rheumatol Inflamm Section Abstract Doc Link 2146129 Disease Relevance 0.06 Pain Relevance 0.26

General Comments

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