INT205587

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Context Info
Confidence 0.28
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.24
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Cyp17a1) lyase activity (Cyp17a1) oxidoreductase activity (Cyp17a1)
endoplasmic reticulum (Cyp17a1)
Anatomy Link Frequency
male-specific 1
Cyp17a1 (Mus musculus)
Pain Link Frequency Relevance Heat
fibrosis 2 22.72 Low Low
imagery 6 5.00 Very Low Very Low Very Low
pain pelvic 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hyperandrogenism 4 65.12 Quite High
Aplasia 29 62.80 Quite High
Syndrome 65 55.88 Quite High
Cystic Fibrosis 2 22.72 Low Low
Disorders Of Galactose Metabolism 1 16.00 Low Low
Disease 3 11.88 Low Low
Androgen Insensitivity 7 5.00 Very Low Very Low Very Low
Hearing Impairment 5 5.00 Very Low Very Low Very Low
Congenital Anomalies 5 5.00 Very Low Very Low Very Low
Infertility 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The WNT4 protein is known to repress male-specific genes such as those encoding steroidogenic enzymes CYP17A1 and HSB3B2, which are essential for the synthesis of testosterone [76].
Negative_regulation (repress) of CYP17A1 in male-specific
1) Confidence 0.28 Published 2007 Journal Orphanet J Rare Dis Section Body Doc Link PMC1832178 Disease Relevance 0.24 Pain Relevance 0

General Comments

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