INT205599

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Context Info
Confidence 0.04
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 0.74
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein modification process (PPT2) lysosome (PPT2)
PPT2 (Homo sapiens)
Pain Link Frequency Relevance Heat
pruritus 4 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
headache 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Muscle Disease 40 90.68 High High
Myoglobinuria 12 77.16 Quite High
Rhabdomyolysis 24 76.44 Quite High
Myositis 8 74.24 Quite High
Arthralgia 12 71.08 Quite High
Pain 16 70.48 Quite High
Thyroid Disease 4 32.32 Quite Low
Hypertension 4 31.60 Quite Low
Diabetes Mellitus 4 31.04 Quite Low
Nicotine Addiction 4 29.72 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Dominant and recessive genetic models of association of statin intolerance with either individual COQ2 SNP genotypes or COQ2 haplotype were evaluated using chi-square analysis.


statin Binding (association) of
1) Confidence 0.04 Published 2007 Journal Lipids Health Dis Section Body Doc Link PMC1832194 Disease Relevance 0 Pain Relevance 0
COQ2 genotypes, based on two single nucleotide polymorphisms (SNP1 and SNP2) and a 2-SNP haplotype, all showed significant associations with statin intolerance.
statin Binding (associations) of
2) Confidence 0.03 Published 2007 Journal Lipids Health Dis Section Abstract Doc Link PMC1832194 Disease Relevance 0.69 Pain Relevance 0
Under recessive models for each, the COQ2 SNP1 and SNP2 genotypes, and also the 2-SNP haplotype all showed significant associations with statin intolerance.
statin Binding (associations) of
3) Confidence 0.03 Published 2007 Journal Lipids Health Dis Section Body Doc Link PMC1832194 Disease Relevance 0.05 Pain Relevance 0
Genetic associations with statin intolerance
statin Binding (associations) of
4) Confidence 0.03 Published 2007 Journal Lipids Health Dis Section Body Doc Link PMC1832194 Disease Relevance 0 Pain Relevance 0

General Comments

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