INT205619

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Context Info
Confidence 0.17
First Reported 2007
Last Reported 2010
Negated 0
Speculated 2
Reported most in Body
Documents 6
Total Number 8
Disease Relevance 1.91
Pain Relevance 0.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

isomerase activity (Renbp)
Anatomy Link Frequency
brain 1
Renbp (Rattus norvegicus)
Pain Link Frequency Relevance Heat
GABAergic 42 99.52 Very High Very High Very High
Arthritis 30 81.32 Quite High
Glutamate receptor 3 77.08 Quite High
Action potential 9 66.64 Quite High
Hippocampus 2 65.72 Quite High
GABA receptor 6 64.72 Quite High
Glutamate 6 50.88 Quite High
Pain 15 50.80 Quite High
primary somatosensory cortex 24 49.64 Quite Low
Thalamus 3 45.80 Quite Low
Disease Link Frequency Relevance Heat
Growth Problems 110 97.84 Very High Very High Very High
Brain Injury 3 97.36 Very High Very High Very High
Aging 95 93.72 High High
Hepatocellular Cancer 2 88.40 High High
Birth Weight 10 81.84 Quite High
Rheumatoid Arthritis 38 81.32 Quite High
Uterine Fibroids 94 77.88 Quite High
Injury 6 74.88 Quite High
Suicidal Behaviour 1 63.40 Quite High
Pre-eclampsia 8 54.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Linear regression was also used to assess the influence of age and gender on SF-36 scores for the general population.
Regulation (influence) of age
1) Confidence 0.17 Published 2007 Journal Orphanet J Rare Dis Section Body Doc Link PMC1838413 Disease Relevance 0.44 Pain Relevance 0.04
Accordingly, as possible alterations of GABAergic processes might play a role in age-related reduction of PPS, we asked whether age-related alterations of PPS and of RFs covary.
Spec (might) Regulation (role) of age associated with gabaergic
2) Confidence 0.13 Published 2010 Journal Cerebral Cortex (New York, NY) Section Body Doc Link PMC2852507 Disease Relevance 0.06 Pain Relevance 0.15
In this study on age-related changes of PPS, we additionally confirmed previous findings about a substantial enlargement of RFs in the hindpaw representation in aged rats (Spengler et al. 1995; Godde et al. 2002; David-Jurgens et al. 2008).
Regulation (changes) of age
3) Confidence 0.13 Published 2010 Journal Cerebral Cortex (New York, NY) Section Body Doc Link PMC2852507 Disease Relevance 0.06 Pain Relevance 0.11
Univariate and multiple linear regressions were used to assess the influence of age, gender, educational level and height on the SF-36 scores for the short stature group.
Regulation (influence) of age associated with growth problems
4) Confidence 0.10 Published 2007 Journal Orphanet J Rare Dis Section Body Doc Link PMC1838413 Disease Relevance 0.37 Pain Relevance 0.09
Several k-means clusters exhibit patterns of up-regulation with age.
Regulation (regulation) of age
5) Confidence 0.08 Published 2010 Journal BMC Genomics Section Body Doc Link PMC3012673 Disease Relevance 0.25 Pain Relevance 0
Besides the influence of age, other conditions such as learning, environmental enrichment, or brain injury affect PPS.
Regulation (influence) of age in brain associated with brain injury
6) Confidence 0.08 Published 2010 Journal Cerebral Cortex (New York, NY) Section Body Doc Link PMC2852507 Disease Relevance 0.19 Pain Relevance 0.10
If and when male and female data do not comport with each other, these sex-differences may inform our assessments of clinical (human) response which may influence the sex and age of rodent models used for pre-clinical testing.
Spec (may) Regulation (influence) of age
7) Confidence 0.05 Published 2010 Journal BMC Genomics Section Body Doc Link PMC3012673 Disease Relevance 0 Pain Relevance 0
Missing data may be related to the true values of gestational age or other birth-related variables, but results were similar when we repeated the analyses assuming women missing gestational age data were not born ?
Regulation (values) of age
8) Confidence 0.02 Published 2010 Journal Environ Health Perspect Section Body Doc Link PMC2854766 Disease Relevance 0.54 Pain Relevance 0.06

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