INT205705

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.07
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.42
Pain Relevance 0.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (P2rx7) cell morphogenesis (P2rx7) mitochondrion organization (P2rx7)
protein complex (P2rx7) transmembrane transport (P2rx7) cytoplasm (P2rx7)
Anatomy Link Frequency
mast cells 3
P2rx7 (Mus musculus)
Il6 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 66 100.00 Very High Very High Very High
cytokine 27 100.00 Very High Very High Very High
antagonist 20 78.00 Quite High
rheumatoid arthritis 7 66.48 Quite High
agonist 10 5.00 Very Low Very Low Very Low
Inflammatory response 7 5.00 Very Low Very Low Very Low
Inflammatory mediators 6 5.00 Very Low Very Low Very Low
Multiple sclerosis 4 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
adenocard 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 79 100.00 Very High Very High Very High
Death 25 99.88 Very High Very High Very High
Hypersensitivity 2 94.64 High High
Diabetic Angiopathy 1 87.56 High High
Diabetes Mellitus 1 83.44 Quite High
Atherosclerosis 3 73.68 Quite High
Fever 2 68.56 Quite High
Rheumatoid Arthritis 7 66.48 Quite High
Arthropathy 1 65.32 Quite High
Cv General 2 Under Development 2 60.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition to inducing cell death, ATP-stimulation of the P2X7R on murine mast cells has been shown to increase the expression of several pro-inflammatory cytokines, including IL-6 and TNF-?
Positive_regulation (stimulation) of P2X7R in mast cells Positive_regulation (increase) of Gene_expression (expression) of IL-6 in mast cells associated with inflammation, death and cytokine
1) Confidence 0.07 Published 2007 Journal J Inflamm (Lond) Section Body Doc Link PMC1838907 Disease Relevance 1.42 Pain Relevance 0.58

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox