INT205710

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Context Info
Confidence 0.02
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.47
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (P2rx7) cell morphogenesis (P2rx7) mitochondrion organization (P2rx7)
protein complex (P2rx7) transmembrane transport (P2rx7) cytoplasm (P2rx7)
CAMP (Homo sapiens)
P2rx7 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 27 98.04 Very High Very High Very High
Inflammation 66 88.48 High High
agonist 10 47.16 Quite Low
antagonist 20 13.12 Low Low
Inflammatory response 7 5.00 Very Low Very Low Very Low
rheumatoid arthritis 7 5.00 Very Low Very Low Very Low
Inflammatory mediators 6 5.00 Very Low Very Low Very Low
Multiple sclerosis 4 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
adenocard 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 40 92.56 High High
INFLAMMATION 79 88.48 High High
Arthritis 3 86.72 High High
Infection 9 72.48 Quite High
Syndrome 1 23.12 Low Low
Targeted Disruption 6 22.48 Low Low
Cryopyrin-associated Periodic Syndromes 1 22.08 Low Low
Death 25 5.00 Very Low Very Low Very Low
Mycobacterial Infection 17 5.00 Very Low Very Low Very Low
Cancer 13 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Such studies indicate that in addition to extracellular ATP, the endogenous, inducible CHDP, LL-37 may activate the P2X7R on key innate immune effector cells to modulate cytokine release.
LL-37 Positive_regulation (activate) of P2X7R associated with cytokine
1) Confidence 0.02 Published 2007 Journal J Inflamm (Lond) Section Body Doc Link PMC1838907 Disease Relevance 0.47 Pain Relevance 0.19

General Comments

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