INT205711

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Context Info
Confidence 0.02
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.92
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (P2rx7) cell morphogenesis (P2rx7) intracellular (IL8)
mitochondrion organization (P2rx7) protein complex (P2rx7) transmembrane transport (P2rx7)
Anatomy Link Frequency
eosinophils 2
P2rx7 (Mus musculus)
IL8 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory response 7 99.76 Very High Very High Very High
cytokine 27 92.52 High High
Inflammation 66 71.60 Quite High
antagonist 20 66.80 Quite High
adenocard 2 51.28 Quite High
agonist 10 36.28 Quite Low
rheumatoid arthritis 7 5.00 Very Low Very Low Very Low
Inflammatory mediators 6 5.00 Very Low Very Low Very Low
Multiple sclerosis 4 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 79 99.36 Very High Very High Very High
Mycobacterial Infection 17 89.84 High High
Apoptosis 40 80.80 Quite High
Death 25 79.28 Quite High
Cancer 13 71.48 Quite High
Disease 12 68.48 Quite High
Chronic Lymphoid Leukemia 3 50.88 Quite High
Brain Injury 5 23.44 Low Low
Necrosis 5 20.24 Low Low
Parkinson's Disease 1 16.08 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The P2X7R has been shown to regulate the release of IL-8 from eosinophils and may be expressed on PMNs, potentially influencing their function.
P2X7R Regulation (regulate) of Localization (release) of IL-8 in eosinophils
1) Confidence 0.02 Published 2007 Journal J Inflamm (Lond) Section Body Doc Link PMC1838907 Disease Relevance 0.92 Pain Relevance 0.33

General Comments

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