INT205713

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Context Info
Confidence 0.03
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.77
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (P2rx7) cell morphogenesis (P2rx7) intracellular (IL8)
mitochondrion organization (P2rx7) protein complex (P2rx7) transmembrane transport (P2rx7)
P2rx7 (Mus musculus)
IL8 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory stimuli 1 98.58 Very High Very High Very High
Inflammatory response 7 93.36 High High
Inflammation 66 90.96 High High
agonist 10 77.64 Quite High
cytokine 27 60.24 Quite High
Multiple sclerosis 4 47.68 Quite Low
antagonist 20 27.92 Quite Low
Inflammatory mediators 6 22.16 Low Low
rheumatoid arthritis 7 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Asthma 3 99.48 Very High Very High Very High
INFLAMMATION 79 98.42 Very High Very High Very High
Occupational Lung Diseases 1 82.32 Quite High
Death 25 58.76 Quite High
Apoptosis 40 49.88 Quite Low
Demyelinating Disease 4 47.68 Quite Low
Encephalitis 1 46.40 Quite Low
Targeted Disruption 6 44.00 Quite Low
Infection 9 38.84 Quite Low
Immune System Diseases 2 14.96 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As ATP can be released upon tissue damage [104] and in response to inflammatory stimuli [49] (both of which may be present in asthma) it is possible that the P2X7R would be activated, resulting in IL-8 production and propagation of the immune response (Figure 3).
Positive_regulation (activated) of P2X7R Positive_regulation (resulting) of Gene_expression (production) of IL-8 associated with asthma and inflammatory stimuli
1) Confidence 0.03 Published 2007 Journal J Inflamm (Lond) Section Body Doc Link PMC1838907 Disease Relevance 0.77 Pain Relevance 0.33

General Comments

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