INT205753

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Context Info
Confidence 0.49
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.53
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
telomere 1
Gm3813 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 7 30.64 Quite Low
tetrodotoxin 12 5.00 Very Low Very Low Very Low
cytokine 9 5.00 Very Low Very Low Very Low
sodium channel 4 5.00 Very Low Very Low Very Low
potassium channel 4 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
Calcium channel 3 5.00 Very Low Very Low Very Low
iatrogenic 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 6 96.60 Very High Very High Very High
Acquired Immune Deficiency Syndrome Or Hiv Infection 5 79.84 Quite High
Injury 7 77.68 Quite High
Hyperplasia 11 75.00 Quite High
Sprains And Strains 6 50.80 Quite High
Obesity 19 50.00 Quite Low
Enzootic Bovine Leukosis 13 50.00 Quite Low
Feline Leukemia 1 44.00 Quite Low
Necrosis 4 38.88 Quite Low
INFLAMMATION 7 30.64 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
g of cDNA was reverse-transcribed using a reverse transcriptase (M-MLV, Gibco BRL) for 90 min at 42°C.
Positive_regulation (using) of reverse transcriptase
1) Confidence 0.49 Published 2010 Journal BMC Cell Biol Section Body Doc Link PMC2867791 Disease Relevance 0 Pain Relevance 0
The pol gene encodes a 80 kDa reverse transcriptase (RT), a RNA-dependent DNA polymerase which is preferentially active in the presence of Mg2+ [122,123].
Positive_regulation (active) of reverse transcriptase
2) Confidence 0.45 Published 2007 Journal Retrovirology Section Body Doc Link PMC1839114 Disease Relevance 0.16 Pain Relevance 0
Several highly proliferative human cells transiently activate telomerase, a ribonucleoprotein with reverse transcriptase activity, to counterbalance replication-associated telomere erosion and to increase stress resistance.
Positive_regulation (activate) of reverse transcriptase in telomere associated with stress
3) Confidence 0.45 Published 2007 Journal Comp Hepatol Section Abstract Doc Link PMC1920532 Disease Relevance 0.37 Pain Relevance 0

General Comments

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