INT205754

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Context Info
Confidence 0.75
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.24
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitosis (Dctn3) chromosome (Dctn3) cytoskeleton (Dctn3)
cell cycle (Dctn3) molecular_function (Dctn3) cell division (Dctn3)
Anatomy Link Frequency
lymphocytes 2
Dctn3 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 16 5.00 Very Low Very Low Very Low
iatrogenic 4 5.00 Very Low Very Low Very Low
palliative 2 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Bioavailability 2 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
Kinase C 2 5.00 Very Low Very Low Very Low
Potency 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 36 99.20 Very High Very High Very High
Disease 38 86.80 High High
Death 20 72.44 Quite High
Leukemia 30 68.72 Quite High
Chronic Lymphoid Leukemia 8 67.60 Quite High
Cancer 44 62.16 Quite High
Lymphocytosis 66 58.64 Quite High
Enzootic Bovine Leukosis 26 50.00 Quite Low
Viral Infection 12 49.56 Quite Low
Infection 52 10.52 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For instance, when lymphocytes are isolated from a BLV-infected sheep and maintained for a few hours in culture, almost all cells expressing the major viral capsid protein p24gag fail to undergo apoptosis (Figure 4).
Gene_expression (expressing) of p24 in lymphocytes associated with apoptosis
1) Confidence 0.75 Published 2007 Journal Retrovirology Section Body Doc Link PMC1839114 Disease Relevance 0.67 Pain Relevance 0
Since lymphocytes synthesizing p24gag are spared from apoptosis ex vivo, p24+BrdU+ double positive cells are not lost during culturing but appear to have been eliminated in vivo.
Gene_expression (synthesizing) of p24 in lymphocytes associated with apoptosis
2) Confidence 0.65 Published 2007 Journal Retrovirology Section Body Doc Link PMC1839114 Disease Relevance 0.57 Pain Relevance 0

General Comments

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