INT205796

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Context Info
Confidence 0.52
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 2.16
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (ERVW-1)
Anatomy Link Frequency
T cell 2
ERVW-1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 21 89.44 High High
addiction 12 82.88 Quite High
headache 14 5.00 Very Low Very Low Very Low
Inflammation 13 5.00 Very Low Very Low Very Low
Pain 9 5.00 Very Low Very Low Very Low
rheumatoid arthritis 3 5.00 Very Low Very Low Very Low
Angina 3 5.00 Very Low Very Low Very Low
iatrogenic 2 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Thyroiditis 117 97.88 Very High Very High Very High
Acquired Immune Deficiency Syndrome Or Hiv Infection 331 84.08 Quite High
Leukemia 19 81.60 Quite High
Thyroid Disease 39 79.40 Quite High
Cancer 23 79.24 Quite High
Infection 111 78.24 Quite High
Lymphocytosis 33 77.12 Quite High
Htlv Types I And Ii 12 71.72 Quite High
Spinal Cord Diseases 5 70.56 Quite High
Graves' Ophthalmopathy 16 64.80 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The virus envelope protein and signals for the mRNA were detected in many of the thyrocytes from one of the patients, by immunohistochemistry and in-situ hybridization respectively.
Transcription (detected) of envelope protein
1) Confidence 0.52 Published 2009 Journal Virol J Section Body Doc Link PMC2654877 Disease Relevance 1.60 Pain Relevance 0
Both Env and Gag response rates were significantly greater than the Pol response rate (p?
Transcription (rates) of Env
2) Confidence 0.37 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2981570 Disease Relevance 0.06 Pain Relevance 0.07
CD8 T cell responses to Env, Nef and Pol were detected after DNA prime - rAd5 boost, with fewer responders seen after the DNA priming.
Transcription (detected) of Env in T cell
3) Confidence 0.15 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2943475 Disease Relevance 0.08 Pain Relevance 0.09
The envelope gene is transcribed as a 5.1 kb mRNA coding for the pr72env precursor [70,80,103,105,106,135].
Transcription (transcribed) of envelope
4) Confidence 0.12 Published 2007 Journal Retrovirology Section Body Doc Link PMC1839114 Disease Relevance 0.34 Pain Relevance 0
CD4 T cell responses to Env, Gag and Nef were detected after DNA prime and after Ad5 boost, but no Pol specific responses were seen.
Transcription (detected) of Env in T cell
5) Confidence 0.07 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2943475 Disease Relevance 0.07 Pain Relevance 0.08

General Comments

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