INT205911

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Context Info
Confidence 0.38
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.47
Pain Relevance 0.99

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Gabrb1) plasma membrane (Gabrb1)
Anatomy Link Frequency
hippocampus 3
cerebral cortex 1
Gabrb1 (Mus musculus)
Pain Link Frequency Relevance Heat
gABA 28 98.80 Very High Very High Very High
GABA receptor 4 98.08 Very High Very High Very High
Hippocampus 54 97.52 Very High Very High Very High
cerebral cortex 52 96.88 Very High Very High Very High
GABAergic 10 84.48 Quite High
Glutamate receptor 2 54.72 Quite High
adenocard 2 46.88 Quite Low
cytokine 8 5.00 Very Low Very Low Very Low
Inflammation 8 5.00 Very Low Very Low Very Low
Analgesic 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Epilepsy 2 93.48 High High
Convulsion 6 75.52 Quite High
Targeted Disruption 16 35.44 Quite Low
INFLAMMATION 10 5.00 Very Low Very Low Very Low
Middle Cerebral Artery Infarction 8 5.00 Very Low Very Low Very Low
Parkinson's Disease 6 5.00 Very Low Very Low Very Low
Aging 4 5.00 Very Low Very Low Very Low
Overdose 2 5.00 Very Low Very Low Very Low
Decapitation 2 5.00 Very Low Very Low Very Low
Cancer 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therefore, our finding that GABRB1 mRNA expression is decreased suggests a downregulation of GABA ionotropic receptor in the hippocampus and cerebral cortex of COX-2-/- mice but not COX-1-/- mice.
Negative_regulation (decreased) of Gene_expression (expression) of GABRB1 mRNA in hippocampus associated with gaba, hippocampus and cerebral cortex
1) Confidence 0.38 Published 2007 Journal Genome Biol Section Body Doc Link PMC1839133 Disease Relevance 0.24 Pain Relevance 0.49
Therefore, our finding that GABRB1 mRNA expression is decreased suggests a downregulation of GABA ionotropic receptor in the hippocampus and cerebral cortex of COX-2-/- mice but not COX-1-/- mice.
Negative_regulation (decreased) of in cerebral cortex Gene_expression (expression) of GABRB1 mRNA in hippocampus associated with gaba, hippocampus and cerebral cortex
2) Confidence 0.13 Published 2007 Journal Genome Biol Section Body Doc Link PMC1839133 Disease Relevance 0.24 Pain Relevance 0.49

General Comments

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