INT205920

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Context Info
Confidence 0.02
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.00
Pain Relevance 2.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Helt) nucleus (Helt) DNA binding (Helt)
Anatomy Link Frequency
interneurons 3
epithelium 2
pyramidal neurons 1
Helt (Mus musculus)
Pain Link Frequency Relevance Heat
GABAergic 83 100.00 Very High Very High Very High
Pyramidal cell 54 100.00 Very High Very High Very High
Anterior cingulate cortex 96 99.68 Very High Very High Very High
Hippocampus 29 92.32 High High
gABA 91 92.00 High High
Neuronal excitability 3 90.60 High High
amygdala 28 86.40 High High
cytokine 4 83.52 Quite High
cerebral cortex 26 39.08 Quite Low
imagery 3 33.36 Quite Low
Disease Link Frequency Relevance Heat
Nicotine Addiction 68 99.98 Very High Very High Very High
Asthma 4 93.92 High High
Pulmonary Disease 2 77.32 Quite High
Convulsion 3 70.60 Quite High
Targeted Disruption 8 68.04 Quite High
Epilepsy 1 27.44 Quite Low
Pruritus 22 5.00 Very Low Very Low Very Low
Anxiety Disorder 16 5.00 Very Low Very Low Very Low
INFLAMMATION 7 5.00 Very Low Very Low Very Low
Generalized Anxiety Disorder 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Morphological and electrophysiological properties of interneurons and pyramidal neurons in the ACC
Regulation (electrophysiological) of Gene_expression (properties) of neurons in interneurons associated with pyramidal cell and anterior cingulate cortex
1) Confidence 0.02 Published 2010 Journal Mol Pain Section Body Doc Link PMC2945970 Disease Relevance 0 Pain Relevance 0.78
Although our observations in the present study are consistent with our previous data [26], it remains to be determined how deletion of COX-2, but not of COX-1, alters the expression of GABAergic system related genes.


Regulation (alters) of Gene_expression (expression) of GABAergic associated with gabaergic
2) Confidence 0.01 Published 2007 Journal Genome Biol Section Body Doc Link PMC1839133 Disease Relevance 0.20 Pain Relevance 0.33
Morphological and electrophysiological properties of interneurons and pyramidal neurons in the ACC
Regulation (electrophysiological) of in pyramidal neurons Gene_expression (properties) of neurons in interneurons associated with pyramidal cell and anterior cingulate cortex
3) Confidence 0.01 Published 2010 Journal Mol Pain Section Body Doc Link PMC2945970 Disease Relevance 0 Pain Relevance 0.78
In the context that cigarette smoking is also associated with mucus hypersecretion, in the present study we asked the question: Does smoking alter the gene expression pattern of GABAergic system genes in the respiratory epithelium?
Regulation (alter) of Gene_expression (expression) of GABAergic in epithelium associated with nicotine addiction and gabaergic
4) Confidence 0.00 Published 2010 Journal Respir Res Section Body Doc Link PMC2988726 Disease Relevance 0.80 Pain Relevance 0.17

General Comments

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