INT205953

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Context Info
Confidence 0.14
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.61
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
pore 1
Shbdp1 (Mus musculus)
Pain Link Frequency Relevance Heat
lidocaine 44 95.68 Very High Very High Very High
action potential duration 24 83.52 Quite High
Action potential 30 78.36 Quite High
Glutamate 4 5.00 Very Low Very Low Very Low
antiarrhythmic agent 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
sodium channel 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypokalemia 83 94.08 High High
Pressure And Volume Under Development 9 92.28 High High
Disease 3 63.80 Quite High
Targeted Disruption 8 58.36 Quite High
Arrhythmogenic Right Ventricular Dysplasia 6 49.04 Quite Low
Syndrome 16 47.44 Quite Low
Ocular Toxicity (including Many Sub-types) 1 15.28 Low Low
Myelodysplastic Syndromes 2 5.00 Very Low Very Low Very Low
Heart Rate Under Development 2 5.00 Very Low Very Low Very Low
Vitelliform Macular Dystrophy 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Single vertical lines indicate the timing of S1 stimuli, and double lines indicate the timing of S2 stimuli
Regulation (timing) of S2
1) Confidence 0.14 Published 2007 Journal Pflugers Arch Section Body Doc Link PMC1839769 Disease Relevance 0.39 Pain Relevance 0.21
However, the rescue experiment alone does not formally prove that dBest1 is the pore-forming subunit of the S2 volume-regulated anion channel (VRAC) because overexpression of an essential regulator or accessory subunit of the channel could have the same effect.
Regulation (regulated) of S2 in pore
2) Confidence 0.01 Published 2008 Journal The Journal of General Physiology Section Body Doc Link PMC2571971 Disease Relevance 0.21 Pain Relevance 0

General Comments

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