INT205957

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Context Info
Confidence 0.08
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 2.57
Pain Relevance 0.60

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Smo) plasma membrane (Smo) cilium (Smo)
cytoplasm (Smo) signal transducer activity (Smo)
Anatomy Link Frequency
stomach 2
Smo (Mus musculus)
Pain Link Frequency Relevance Heat
Neuritis 24 96.40 Very High Very High Very High
Inflammation 12 87.68 High High
Demyelination 1 59.76 Quite High
Peripheral nervous system 5 56.16 Quite High
cytokine 13 5.36 Low Low
Multiple sclerosis 5 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Foreign Bodies 16 100.00 Very High Very High Very High
Repression 3 99.28 Very High Very High Very High
Cancer 33 99.06 Very High Very High Very High
Experimental Autoimmune Neuritis 24 96.40 Very High Very High Very High
INFLAMMATION 13 87.68 High High
Syndrome 19 80.64 Quite High
Medulloblastoma 10 77.68 Quite High
Disease 24 67.44 Quite High
Immunization 2 66.68 Quite High
Sprains And Strains 1 63.80 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
And apoE-deficient mice were shown to suffer impaired BNB and BBB, which might be one of the reasons why apoE-deficient mice underwent more severe EAN [132, 133].
Negative_regulation (impaired) of BNB associated with neuritis
1) Confidence 0.08 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2825561 Disease Relevance 1.03 Pain Relevance 0.60
Shh binds to the tumor repression gene Patched (Ptc1), releasing its suppression of Smoothened (Smo), which activates Gli transcription factors.
Negative_regulation (suppression) of Smoothened associated with cancer and repression
2) Confidence 0.04 Published 2007 Journal BMC Syst Biol Section Body Doc Link PMC1839891 Disease Relevance 0.71 Pain Relevance 0
For example, a "removal of a foreign body from the stomach by gastrotomy" procedure involves the "removal" of a "foreign body" (not of a stomach) and the "incision" of a "stomach" (not of a foreign body).
Negative_regulation (removal) of foreign body in stomach associated with foreign bodies
3) Confidence 0.01 Published 2008 Journal BMC Med Inform Decis Mak Section Body Doc Link PMC2582796 Disease Relevance 0.42 Pain Relevance 0
For example, a "removal of a foreign body from the stomach by gastrotomy" procedure involves the "removal" of a "foreign body" (not of a stomach) and the "incision" of a "stomach" (not of a foreign body).
Negative_regulation (removal) of foreign body in stomach associated with foreign bodies
4) Confidence 0.01 Published 2008 Journal BMC Med Inform Decis Mak Section Body Doc Link PMC2582796 Disease Relevance 0.41 Pain Relevance 0

General Comments

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