INT205959

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Context Info
Confidence 0.12
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.72
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (SHH, SMOX) small molecule metabolic process (SMOX) Golgi apparatus (SHH)
endoplasmic reticulum (SHH) embryo development (SHH) cytoplasm (SMOX)
SHH (Homo sapiens)
SMOX (Homo sapiens)
Pain Link Frequency Relevance Heat
tolerance 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 32 100.00 Very High Very High Very High
Repression 3 100.00 Very High Very High Very High
Medulloblastoma 10 78.08 Quite High
Disease 3 32.52 Quite Low
Brain Tumor 2 30.64 Quite Low
Apoptosis 3 5.00 Very Low Very Low Very Low
Metastasis 1 5.00 Very Low Very Low Very Low
Cerebral Palsy 1 5.00 Very Low Very Low Very Low
Congenital Anomalies 1 5.00 Very Low Very Low Very Low
Disease Progression 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Shh binds to the tumor repression gene Patched (Ptc1), releasing its suppression of Smoothened (Smo), which activates Gli transcription factors.
Shh Binding (binds) of Smo associated with cancer and repression
1) Confidence 0.12 Published 2007 Journal BMC Syst Biol Section Body Doc Link PMC1839891 Disease Relevance 0.72 Pain Relevance 0

General Comments

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