INT20597

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Context Info
Confidence 0.65
First Reported 1981
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 5
Total Number 5
Disease Relevance 1.07
Pain Relevance 1.72

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleolus (Hrh1) plasma membrane (Hrh1) nucleus (Hrh1)
cytoplasm (Hrh1) signal transducer activity (Hrh1)
Anatomy Link Frequency
neuronal 1
cerebral cortex 1
mast cell 1
Hrh1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Dopamine 4 100.00 Very High Very High Very High
agonist 3 100.00 Very High Very High Very High
Serotonin 2 100.00 Very High Very High Very High
antagonist 2 100.00 Very High Very High Very High
opiate 1 100.00 Very High Very High Very High
Neurotransmitter 5 99.98 Very High Very High Very High
cerebral cortex 2 98.76 Very High Very High Very High
GABA receptor 1 97.80 Very High Very High Very High
qutenza 5 97.38 Very High Very High Very High
interstitial cystitis 4 94.64 High High
Disease Link Frequency Relevance Heat
Gastric Fistula 1 99.08 Very High Very High Very High
Interstitial Cystitis 4 94.64 High High
Manic Depressive Disorder 40 94.36 High High
Recurrence 3 92.68 High High
Depression 7 92.24 High High
Mental Disorders 1 76.72 Quite High
Schizophrenia 44 50.00 Quite Low
Weight Gain 26 15.12 Low Low
Psychosis 15 5.00 Very Low Very Low Very Low
Sleep Disorders 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The effect of perivagal capsaicin treatment on gastric acid secretion induced by the histamine H2 receptor agonist, dimaprit dihydrochloride, and the effect of the histamine H1 receptor agonist, 2-thiazolylethylamine dihydrochloride, on gastric acid secretion were studied in acute gastric fistula rats anesthetized with urethane.
Localization (secretion) of histamine H1 associated with qutenza, gastric fistula and agonist
1) Confidence 0.65 Published 1990 Journal Eur. J. Pharmacol. Section Abstract Doc Link 2149706 Disease Relevance 0.10 Pain Relevance 0.45
Hydroxyzine is a piperazine, tricyclic, H1-receptor antagonist with unique properties, especially the inhibition of mast cell and neuronal secretion.
Localization (secretion) of H1-receptor in neuronal associated with antagonist
2) Confidence 0.64 Published 1994 Journal Urol. Clin. North Am. Section Abstract Doc Link 8284834 Disease Relevance 0.17 Pain Relevance 0.22
Hydroxyzine is a piperazine, tricyclic, H1-receptor antagonist with unique properties, especially the inhibition of mast cell and neuronal secretion.
Localization (secretion) of H1-receptor in mast cell associated with antagonist
3) Confidence 0.22 Published 1994 Journal Urol. Clin. North Am. Section Abstract Doc Link 8284834 Disease Relevance 0.17 Pain Relevance 0.22
Olanzapine is a thienobenzodiazepine analog that binds to a large number of neurotransmitter receptors, including the dopamine D1, D2, and D4 receptors, serotonin 5-HT2A, 5-HT2C, 5-HT6, and 5-HT3 receptors, histamine H1 receptor, muscarinic receptors, ?
Localization (receptors) of histamine H1 receptor associated with dopamine, neurotransmitter and serotonin
4) Confidence 0.08 Published 2010 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2987508 Disease Relevance 0.63 Pain Relevance 0.38
Our observations include the localization of muscarinic cholinergic, benzodiazepine, opiate, neurotensin, histamine-H1, alpha-adrenergic, beta-adrenergic, and high-affinity GABA receptors in the cerebral cortex.
Localization (localization) of histamine-H1 in cerebral cortex associated with gaba receptor, opiate and cerebral cortex
5) Confidence 0.05 Published 1981 Journal J. Histochem. Cytochem. Section Abstract Doc Link 6270206 Disease Relevance 0 Pain Relevance 0.45

General Comments

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