INT205985

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Context Info
Confidence 0.00
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.73
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Ptn) nucleolus (Trib3) endoplasmic reticulum (Ptn)
nucleus (Trib3) enzyme binding (Trib3) kinase activity (Trib3)
Anatomy Link Frequency
neuronal 3
Ptn (Rattus norvegicus)
Trib3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Paracetamol 99 5.00 Very Low Very Low Very Low
Angina 15 5.00 Very Low Very Low Very Low
Bile 12 5.00 Very Low Very Low Very Low
Analgesic 6 5.00 Very Low Very Low Very Low
Inflammation 6 5.00 Very Low Very Low Very Low
Pain 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Necrosis 87 74.00 Quite High
Stress 12 48.40 Quite Low
Heart Disease 39 5.00 Very Low Very Low Very Low
Toxicity 15 5.00 Very Low Very Low Very Low
Injury 15 5.00 Very Low Very Low Very Low
Hepatotoxicity 12 5.00 Very Low Very Low Very Low
Cv General 3 Under Development 12 5.00 Very Low Very Low Very Low
Hyperplasia 6 5.00 Very Low Very Low Very Low
Breast Cancer 6 5.00 Very Low Very Low Very Low
INFLAMMATION 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The high dosed 6 hrs rats differed from the high dosed 18, 24 and 48 hrs rats by a small cluster of genes that include an activator (Mitogen activated protein kinase kinase kinase 12 [Map3k12]) of the c-Jun N-terminal kinase (JNK) pathway, a transactivator of thyroid-stimulating hormone beta, and a regulator of neuronal differentiation and development.



Mitogen Positive_regulation (activated) of kinase in neuronal
1) Confidence 0.00 Published 2007 Journal BMC Syst Biol Section Body Doc Link PMC1839893 Disease Relevance 0.24 Pain Relevance 0
The high dosed 6 hrs rats differed from the high dosed 18, 24 and 48 hrs rats by a small cluster of genes that include an activator (Mitogen activated protein kinase kinase kinase 12 [Map3k12]) of the c-Jun N-terminal kinase (JNK) pathway, a transactivator of thyroid-stimulating hormone beta, and a regulator of neuronal differentiation and development.



Mitogen Positive_regulation (activated) of kinase in neuronal
2) Confidence 0.00 Published 2007 Journal BMC Syst Biol Section Body Doc Link PMC1839893 Disease Relevance 0.24 Pain Relevance 0
The high dosed 6 hrs rats differed from the high dosed 18, 24 and 48 hrs rats by a small cluster of genes that include an activator (Mitogen activated protein kinase kinase kinase 12 [Map3k12]) of the c-Jun N-terminal kinase (JNK) pathway, a transactivator of thyroid-stimulating hormone beta, and a regulator of neuronal differentiation and development.



Mitogen Positive_regulation (activated) of kinase in neuronal
3) Confidence 0.00 Published 2007 Journal BMC Syst Biol Section Body Doc Link PMC1839893 Disease Relevance 0.24 Pain Relevance 0

General Comments

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