INT206059

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Context Info
Confidence 0.02
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.16
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL6, INS) extracellular region (IL6, INS) small molecule metabolic process (INS)
aging (IL6) carbohydrate metabolic process (INS) cell-cell signaling (INS)
Anatomy Link Frequency
fat cells 1
IL6 (Homo sapiens)
INS (Homo sapiens)
Pain Link Frequency Relevance Heat
tolerance 3 97.04 Very High Very High Very High
cytokine 27 89.20 High High
Inflammatory marker 3 62.08 Quite High
Inflammation 54 50.00 Quite Low
antagonist 1 49.72 Quite Low
Arthritis 10 5.00 Very Low Very Low Very Low
Inflammatory response 8 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
chemokine 3 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Insulin Resistance 9 100.00 Very High Very High Very High
Obesity 9 100.00 Very High Very High Very High
Diabetes Mellitus 33 98.64 Very High Very High Very High
Impaired Glucose Tolerance 3 97.04 Very High Very High Very High
Necrosis 5 66.72 Quite High
Cancer 18 66.36 Quite High
INFLAMMATION 68 62.08 Quite High
Atherosclerosis 44 61.72 Quite High
Aging 21 50.00 Quite Low
Cardiovascular Disease 20 45.36 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Growing evidence suggests that IL-6 is not only produced by fat cells but is also capable of inducing insulin resistance in these cells.
IL-6 Positive_regulation (inducing) of insulin in fat cells associated with obesity and insulin resistance
1) Confidence 0.02 Published 2007 Journal Immun Ageing Section Body Doc Link PMC1845171 Disease Relevance 1.16 Pain Relevance 0.16

General Comments

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