INT206078

Context Info Confidence 0.00 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0.09

cytosol (FDPS, GGPS1) small molecule metabolic process (FDPS, GGPS1) cytoplasm (FDPS, GGPS1) mitochondrion (FDPS) nucleolus (FDPS) nucleus (FDPS)

FDPS (Homo sapiens) GGPS1 (Homo sapiens)

Pain Link Frequency Relevance Heat Potency 2 87.36 Inflammation 54 50.00 metalloproteinase 2 32.00 cytokine 27 5.00 Arthritis 10 5.00 Inflammatory response 8 5.00 Inflammatory marker 3 5.00 Pain 3 5.00 tolerance 3 5.00 chemokine 3 5.00

Disease Link Frequency Relevance Heat INFLAMMATION 68 50.00 Aging 21 50.00 Atherosclerosis 44 5.00 Osteoporosis 35 5.00 Diabetes Mellitus 33 5.00 Cardiovascular Disease 20 5.00 Disease 19 5.00 Cancer 18 5.00 Hypercalcemia 11 5.00 Arthritis 10 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Inhibition of FPP synthase prevents the formation of FPP and its derivative GGPP.

FPP Binding (formation) of GGPP

1) Confidence 0.00 Published 2007 Journal Immun Ageing Section Body Doc Link PMC1845171 Disease Relevance 0 Pain Relevance 0.09

General Comments

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