INT206082

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Context Info
Confidence 0.07
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.30
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL6, CCL2) aging (IL6, CCL2) extracellular region (IL6, CCL2)
signal transduction (CCL2) cell adhesion (CCL2) cytoskeleton organization (CCL2)
IL6 (Homo sapiens)
CCL2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 54 50.00 Quite Low
cytokine 27 5.00 Very Low Very Low Very Low
Arthritis 10 5.00 Very Low Very Low Very Low
Inflammatory response 8 5.00 Very Low Very Low Very Low
Inflammatory marker 3 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
tolerance 3 5.00 Very Low Very Low Very Low
chemokine 3 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Thrombosis 1 81.24 Quite High
Dyslipidemia /

Combined Dyslipidemia

1 79.60 Quite High
Coagulation Disorder 2 79.40 Quite High
Atherosclerosis 44 54.96 Quite High
INFLAMMATION 68 50.00 Quite Low
Aging 21 50.00 Quite Low
Adhesions 7 25.76 Quite Low
Hyperlipoproteinemia Type Ii 5 13.52 Low Low
Osteoporosis 35 5.00 Very Low Very Low Very Low
Diabetes Mellitus 33 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
IL-6 also stimulated MCP-1 protein production and DNA synthesis dose dependently. 50 microM of AG490, a specific JAK 2 inhibitor, partially inhibited STAT 3 activation and MCP-1 production, with near complete inhibition of DNA synthesis [91].
IL-6 Positive_regulation (stimulated) of Gene_expression (production) of MCP-1
1) Confidence 0.07 Published 2007 Journal Immun Ageing Section Body Doc Link PMC1845171 Disease Relevance 0.22 Pain Relevance 0

General Comments

This test has worked.

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